Patients with new coronavirus pneumonia will develop some symptoms after infection, and some people may progress from mild symptoms to incredibly severe symptoms.
In a new article in the journal Science, the perspectives of frontline doctors fighting COVID-19 revealed how the disease evolved from negligible discomfort to life-threatening organ failure.
The main mode of transmission of the new coronavirus is through droplets in the air. This new coronavirus attacks the binding site on the cell that has the ACE2 receptor.
Initially, the symptoms were mild or completely absent, and a person did not even know that he had been infected. Then, the virus will enter the lungs.
The fragile tissues in the lungs were lined with ACE2 receptors that the virus loved, and the virus attack began.
When white blood cells begin to fight infection, the battle between the virus and the immune system hinders the lungs' ability to supply oxygen to the blood.
Frontline leukocytes release inflammatory molecules called chemokines, which in turn will call for more immune cells to target and kill virus-infected cells, leaving fluid and dead cells-pustules.
This is the basic pathology of pneumonia, and the corresponding symptoms are: cough, fever, shortness of breath, etc.
At this time, the patient will encounter a fork in the road. From this moment on, some patients, with the help of oxygen therapy and rest, turned from crisis to safety and began to recover.
However, other people will have more serious complications, such as acute respiratory distress syndrome (ARDS), when the lungs cannot provide enough oxygen to sustain life.
These patients often rely on ventilators to maintain their lives. Sadly, a considerable number of them cannot overcome the virus.
Even in patients whose lung reactions are not fatal, they can cause damage to other organs, including the heart and kidneys.
Doctors are still trying to explain how the virus attacks the heart, but people think that the blood clot produced by the virus may be the key.
This can also explain the damaging effects of the virus on the kidneys, because the kidneys filter the blood, and when the blood clots accumulate, the kidneys are blocked by the blood clots.
In addition, how the new coronavirus affects the brain is another major problem that healthcare workers are trying to solve.
Quite a few patients have seizures and swelling of the brain, but it is unclear how the virus attacks the brainstem or neurocortex, and these two sites have ACE2 receptors, and the virus may attach to these two sites, nor Know whether the virus will spread to the cerebrospinal fluid that protects many important parts of the central nervous system.
It is possible that the virus's effect on the blood eventually led to a reaction in the brain, because blood clots may cause swelling and trigger any serious series of neurological symptoms.
After all, it is clear that there are still many unsolved mysteries about this new coronavirus and how it attacks the human body.
Why can some patients survive, while others are getting worse quickly?
This question may take some time to get an answer, but there is no shortage of doctors and scientists working around the clock to answer this question.
Special Report: Fighting The New Coronavirus
