The first Covid-19 new coronavirus vaccines developed in China have entered the clinical stage. A few days ago, researchers released detailed data on the inactivated vaccine, and the result showed that it can neutralize 10 new coronaviruses.
The best way to deal with the Covid-19 new coronavirus epidemic is vaccines. Currently, countries are accelerating vaccine research and development.
Two kinds of vaccines in China have entered the clinical stage. Among them, the recombinant vaccine led by the academician Chen Wei, a member of the Chinese Academy of Engineering and the researcher of the Academy of Military Medical Sciences, has entered the second phase of the recombinant coronavirus (adenovirus vector) vaccine clinical trials.
The other vaccine is an inactivated vaccine developed by the Wuhan Biological Products Research Institute under Sinopharm Group, Sinovac Research & Development Co., Ltd. and relevant scientific research institutions, and directly entered the phase I and II combined clinical trials.
At present, there is no detailed data on the new coronavirus vaccines developed globally, except for Sinovac's inactivated vaccine.
The Institute of Medical Laboratory Animals of the Chinese Academy of Medical Sciences recently published an article on the protection of the Covid-19 inactivated vaccine in bioRxiv, revealing the vaccine's specific effects.
According to a summary by health blogger @子陵在听歌 on Weibo, after animal inoculation, the Covid-19 inactivated vaccine is not only safe but also obtained high-titer SARS-CoV-2 specific IgG antibodies.
Here is an auto-translation of the blogger's Weibo content:
After 6 weeks of inoculation, their serum neutralization titer was as high as EC50 10e4, which was significantly higher than that of the recovered patients’ plasma reported in the previous literature, and their immune serum response was broad-spectrum, which neutralized 10 different SARS-CoV-2 strains.
Overall, this inactivated vaccine is a very successful development, and the method of evaluating the vaccine is also very comprehensive.
In addition to serum neutralization, T cell response, histology, and more importantly, the protection against attack is very efficient and showed good security.